First download the guix qcow image here: https://guix.gnu.org/manual/en/html_node/Running-Guix-in-a-VM.html Then in the same dir put the following in a bash script: #+begin_src sh #!/usr/bin/env bash qemu-system-x86_64 \ -nic user,model=virtio-net-pci \ -enable-kvm -m 2048 \ -device virtio-blk,drive=myhd \ -drive if=none,file=guix-system-vm-image-1.4.0.x86_64-linux.qcow2,id=myhd \ -device virtio-serial \ -chardev socket,path=/tmp/foo,server=on,wait=off,id=foo \ -device virtserialport,chardev=foo,name=org.fedoraproject.port.0 #+end_src And then do : #+begin_src sh ls -alh /sys/class/virtio-ports/ #+end_src According to this link there should be something but I'dont see anything on my end